Just like the previous chamber, there's a door that won't open until a corresponding button is pressed.
What do I need to do?
Look around the room - the glass walls are there to make sure you can see everything you need to see.
Hmm...
A blue portal changes position every few seconds.
How does that help me?
If you step through an orange portal, you'll come out of a blue one, and vice versa.
Look for a blue portal.
Hmm...
You can find out where a portal goes just by looking through it.
Walk through the portal when it shows a room with a cube.
Help me out.
Pick up the cube, and take it back through the portal with you.
You should then enter the button room and drop the cube on top of it.
What now?
Step through the portal once again - don't worry if it disappeared, it'll come back around eventually - and wait in the main room until you can see the opened door through the portal.
Once that's happened, you can head through it and enjoy the elevator ride to chamber 2!
Guide help
This is the low-spoiler guide for "Unlocking the door" puzzle in Portal. Unlike in normal walkthrough, you get gradual hints on how to solve the puzzle. Click the big button below to see your first hint. If the hint contains a spoiler, you will be warned about it before clicking.
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