The alien's power-up has had disastrous consequences for the walls and lights of the place.
A voice calling for help came from the right - the nearby hallway would be a good place to start.
There's not a lot we can do about that fire for now - and not many obvious places to go.
The woman trapped behind the door doesn't have much useful information either.
Try to find an alternate route - a way to get around (or away from) the fire.
Is there anything you could move to reveal a new path?
Use your wrench on the air duct near the fire to loosen it, and access the laboratory.
The laboratory has a whole lot of science-y looking things in it.
See if any of it can help put the fire out.